Article
Suppression of ras-mediated transformation. Differential expression of genes encoding extracellular matrix proteins in normal, transformed and revertant cells.
Advances in enzyme regulation - 1 Jan 1993
Hajnal A, Klemenz R, Schäfer R
Abstract excerpt
A subtraction hybridization technique was used to identify genes specifically expressed in phenotypic revertants derived from cells transformed by the H-ras oncogene. The expression of genes coding for components of the extracellular matrix appears to be frequently down-regulated in transformed c...
Topics
- Animals
- Base Sequence
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Collagen
- DNA
- Down-Regulation
- Gene Expression Regulation
- Genes, ras
- Humans
- Mice
- Molecular Sequence Data
- Phenotype
- Procollagen
- Rats
- Sequence Alignment
- Sequence Tagged Sites