Article
Molecular interaction between K-Ras and H-REV107 in the Ras signaling pathway.
Biochemical and biophysical research communications - 16 Sept 2017
Han Chang Woo, Jeong Mi Suk, Jang Se Bok
Abstract excerpt
Ras proteins are small GTPases that serve as master moderators of a large number of signaling pathways involved in various cellular processes. Activating mutations in Ras are found in about one-third of cancers. H-REV107, a K-Ras binding protein, plays an important role in determining K-Ras function. H-REV107 is a member of the HREV107 family of class II tumor suppressor genes and a growth inhibitory Ras target...
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