Article
Activation of tumor suppressor genes in nontumorigenic revertants of the HeLa cervical carcinoma cell line.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jun 1996
Boylan M O, Athanassiou M, Houle B, Wang Y, Zarbl H
Abstract excerpt
Two nontransformed revertants of HeLa cells, designated HA and HF, were isolated using a selection procedure based on prolonged retention of the fluorescent dye rhodamine 123 within the mitochondria of HeLa (ATCC CCL2) cells versus normal epithelial cells. Unlike the parental HeLa cells, the revertants expressed markedly reduced levels of the bone-liver-kidney, placental, and intestinal isoforms of alkaline...
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