Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP53 mutation analyses on breast carcinomas: a study of paraffin-embedded archival material.

British journal of cancer - 1 Aug 1996

Gretarsdottir S, Tryggvadottir L, Jonasson J G, Sigurdsson H, Olafsdottir K, Agnarsson B A, Ogmundsdottir H, Eyfjörd J E

Abstract excerpt

The aim of this investigation was to examine the possibility of analysing TP53 mutations in archival paraffin-embedded material with the constant denaturant gel electrophoresis (CDGE) method. We extracted DNA from 193 archival primary breast carcinoma samples, diagnosed in 1981-83; further analysis was possible for 186 of these. TP53 mutations in exons 5-8 were detected with CDGE in 30 samples (16.1%) and 17 of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to DNA Mutational Analysis

Share to DNA, Neoplasm

Share to Genes, p53

Share to Immunohistochemistry

Source

Open in PubMed Open full text

Identifiers

PMID: 8761369
DOI: 10.1038/bjc.1996.400
PMCID: PMC2074687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP53 mutation analyses on breast carcinomas: a study of paraffin-embedded archival material.PMID 8761369Read ↗

Prognostic significance of TP53 alterations in breast carcinoma.Semantic proximity Read ↗

Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor.Semantic proximity Read ↗

TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis.Semantic proximity Read ↗

Genomic instability and poor prognosis associated with abnormal TP53 in breast carcinomas. Molecular and immunohistochemical analysis.Semantic proximity Read ↗

TP53 mutation patterns in breast cancers: searching for clues of environmental carcinogenesis.Semantic proximity Read ↗

Screening for TP53 mutations in patients and tumours from 109 Swedish breast cancer families.Semantic proximity Read ↗

TP53 abnormalities and genetic instability in breast cancer.Semantic proximity Read ↗

TP53Mutation is an Independent Prognostic Marker for Poor Outcome in Both Node-negative and Node-positive Breast CancerSemantic proximity Read ↗

Molecular and immunohistochemical analysis of p53 mutations in scrapings and tissue from preinvasive and invasive breast cancer.Semantic proximity Read ↗

p53 gene mutations and steroid receptor status in breast cancer. Clinicopathologic correlations and prognostic assessment.Semantic proximity Read ↗

TP53 gene mutations and protein accumulation in primary vaginal carcinomas.Semantic proximity Read ↗

TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.