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Article

TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis.

European journal of cancer (Oxford, England : 1990) - 1 Oct 1995

Thorlacius S, Thorgilsson B, Björnsson J, Tryggvadottir L, Börresen A L, Ogmundsdottir H M, Eyfjörd J E

Abstract excerpt

Abnormalities in the TP53 tumour suppressor gene were evaluated in 106 unselected breast carcinomas and compared to clinical outcome of the disease. Tumours were screened for p53 abnormalities using immunohistochemical staining and polymerase chain reaction-constant denaturant gel electrophoresis...

Topics

Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Breast Neoplasms
Female
Follow-Up Studies
Genes, p53
Humans
Immunoenzyme Techniques
Middle Aged
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Proteins

Prognosis

Survival Rate

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8541113
DOI: 10.1016/0959-8049(95)00399-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8541113-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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