Article
Analysis and clinical implications of p53 gene mutations and human papillomavirus type 16 and 18 infection in primary adenocarcinoma of the uterine cervix.
The American journal of pathology - 1 Apr 1998
Tenti P, Pavanello S, Padovan L, Spinillo A, Vesentini N, Zappatore R, Migliora P, Zara C, Ranzani G N, Carnevali L
Abstract excerpt
Mutant p53 is frequently detected in endometrial and ovarian carcinoma, but it is rare in cervical cancers. Previous reports focused on cervical squamous cell carcinoma, whereas cervical adenocarcinoma was given little attention. We searched for p53 gene mutations in 74 primary cervical adenocarcinomas with known human papillomavirus (HPV) status. Our aim was to evaluate the prevalence of p53 mutations and to...
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