Article
Identification of a 910-kb region of common allelic loss in chromosome bands 16q24.1-q24.2 in human lung cancer.
Genes, chromosomes & cancer - 1 May 1998
Sato M, Mori Y, Sakurada A, Fukushige S, Ishikawa Y, Tsuchiya E, Saito Y, Nukiwa T, Fujimura S, Horii A
Abstract excerpt
To understand the molecular pathogenesis of human lung cancer, we analyzed allelic deletions on the long arm of chromosome 16 by PCR amplification of microsatellite markers. A total of 203 lung cancer specimens (78 squamous cell carcinomas and 125 adenocarcinomas) were analyzed. In both cell type...
Topics
- Adult
- Aged
- Alleles
- Chromosome Banding
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 16
- Female
- Humans
- In Situ Hybridization, Fluorescence
- Loss of Heterozygosity
- Lung Neoplasms
- Male
- Middle Aged
