Article
A genome-wide map showing common regions of loss of heterozygosity/allelic imbalance in breast cancer.
Cancer research - 15 Jul 2000
Osborne R J, Hamshere M G
Abstract excerpt
We report here a new framework map that integrates data from 143 studies on the loss of heterozygosity/allelic imbalance in breast cancer. Full details of these loss of heterozygosity maps can be found at the web site (http://www.nottingham.ac.uk/pdzmgh/loh/) that accompanies this report. By combining results from these data, we have also been able to highlight and identify minimum commonly deleted regions on...
Topics
- Alleles
- BRCA2 Protein
- Breast Neoplasms
- Chromosome Mapping
- Female
- Genes, BRCA1
- Genome, Human
- Humans
- Loss of Heterozygosity
- Neoplasm Proteins
- Polymorphism, Restriction Fragment Length
