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Article

Molecular differences between human and experimental pancreaticobiliary diversion-induced rat pancreatic neoplasia.

Gut - 1 May 1991

Hall P A, Lemoine N R, Murphy G, Dowling R H

Abstract excerpt

A series of molecular changes are now known to be seen in human pancreatic neoplasia, including the very frequent mutational activation of Kirsten ras oncogene at codon 12, overexpression of the epidermal growth factor receptor, and abnormalities of c-erbB-2 expression. In order to determine whether similar changes can be seen in animal models of pancreatic cancer a molecular analysis of tumours induced in rats...

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Identifiers

PMID: 2040477
DOI: 10.1136/gut.32.5.533
PMCID: PMC1378932

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Source receipt: pubmed, retrieved 7 Sept 2026.

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