Article
Molecular differences between human and experimental pancreaticobiliary diversion-induced rat pancreatic neoplasia.
Gut - 1 May 1991
Hall P A, Lemoine N R, Murphy G, Dowling R H
Abstract excerpt
A series of molecular changes are now known to be seen in human pancreatic neoplasia, including the very frequent mutational activation of Kirsten ras oncogene at codon 12, overexpression of the epidermal growth factor receptor, and abnormalities of c-erbB-2 expression. In order to determine whet...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biliopancreatic Diversion
- ErbB Receptors
- Gene Expression Regulation
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Pancreatic Neoplasms
- Polymerase Chain Reaction
- Rats
- Rats, Inbred Strains