Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing.

Cancer - 1 Sept 1990

Tada M, Yokosuka O, Omata M, Ohto M, Isono K

Abstract excerpt

Ras gene is one of the oncogenes most commonly detected in human cancers and consists of three families (H-ras, K-ras, N-ras) that are converted to active oncogenes by point mutations occurring in codon 12, 13, or 61. The authors analyzed mutations of these codons in 12 extrahepatic bile duct carcinomas, nine gallbladder carcinomas, and 20 pancreatic tumors (18 pancreatic adenocarcinomas and two islet cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Codon
Share to DNA Probes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Mutation

Share to Pancreatic Neoplasms

Share to Polymerase Chain Reaction

Share to RNA, Messenger

Source

Identifiers

PMID: 2167148
DOI: 10.1002/1097-0142(19900901)66:5<930::aid-cncr2820660519>3.0.co;2-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing.PMID 2167148Read ↗

Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing.Semantic proximity Read ↗

Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma.Semantic proximity Read ↗

Detection of codon 12 mutation in the K-ras oncogene in pancreatic tumors.Semantic proximity Read ↗

[Detection of ras gene mutations of primary hepatic malignant tumors by polymerase chain reaction and direct sequencing method].Semantic proximity Read ↗

Distinguishing pancreatic carcinoma from other periampullary carcinomas by analysis of mutations in the Kirsten-ras oncogene.Semantic proximity Read ↗

K-ras codon 12 and p53 mutations in biopsy specimens and bile from biliary tract cancers.Semantic proximity Read ↗

K-Ras mutations and benign pancreatic disease.Semantic proximity Read ↗

Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction.Semantic proximity Read ↗

Patterns of K-ras codon 12 and 13 mutations found in pancreatic adenocarcinoma of 30 Chinese patients by microdissection, PCR and direct sequencing.Semantic proximity Read ↗

Crude isolation of DNA from unselected human pancreatic tissue and amplification by the polymerase chain reaction of Ki-ras oncogene to detect point mutations in pancreatic cancer.Semantic proximity Read ↗

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.Semantic proximity Read ↗

Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.