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Article

Slowed receptor trafficking in mutant CHO lines of the End1 and End2 complementation groups.

Journal of cellular physiology - 1 Jan 1994

Johnson L S, Presley J F, Park J C, McGraw T E

Abstract excerpt

A mutant Chinese hamster ovary cell line with nonconditional kinetic defects in receptor internalization and recycling was isolated, based on selection for resistance to a transferrin-diphtheria toxin conjugate and screening for aberrant receptor trafficking. The 12-4 cell line internalizes transferrin at approximately 75% of the parental rate and recycles transferrin back to the cell surface at approximately 55%...

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Identifiers

PMID: 8263026
DOI: 10.1002/jcp.1041580105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Slowed receptor trafficking in mutant CHO lines of the End1 and End2 complementation groups.PMID 8263026Read ↗

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