Recovery of function in Chinese hamster ovary cell mutants with temperature-sensitive defects in vacuolar acidification.

doi:10.1083/jcb.110.4.1023

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Article

Recovery of function in Chinese hamster ovary cell mutants with temperature-sensitive defects in vacuolar acidification.

The Journal of cell biology - 1 Apr 1990

Roff C F, Hall C W, Robbins A R

Abstract excerpt

After 4 h at 41 degrees C, B3853 and M311, temperature-sensitive Chinese hamster ovary cell End1 and End2 mutants, respectively, are pleiotropically defective in endocytosis and trans-Golgi network-associated activities (Roff, C. F., R. Fuchs, I. Mellman, and A. R. Robbins. 1986. J. Cell Biol. 10...

Topics

Animals
Bacterial Toxins
Cell Line
Cricetinae
Cricetulus
Female
Hydrogen-Ion Concentration
Iron
Kinetics
Mannosephosphates
Mutation
Ovary
Receptor, IGF Type 2
Receptors, Cell Surface
Temperature
Transferrin
Vacuoles

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