Article
Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells.
Nature cell biology - 1 Jun 2001
Lin S X, Grant B, Hirsh D, Maxfield F R
Abstract excerpt
RME-1 is an Eps15-homology (EH)-domain protein that was identified in a genetic screen for endocytosis genes in Caenorhabditis elegans. When expressed in a CHO cell line, the worm RME-1 protein and a mouse homologue are both associated with the endocytic recycling compartment. Here we show that expression of a dominant-negative construct with a point mutation near the EH domain results in redistribution of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
