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Article

Biosynthesis of lysosomal enzymes in cells of the End3 complementation group conditionally defective in endosomal acidification.

Somatic cell and molecular genetics - 1 Mar 1991

Park J E, Draper R K, Brown W J

Abstract excerpt

Various aspects of lysosome biogenesis have been studied in Chinese hamster ovary (CHO) cells of the End3 complementation group (designated G.7.1 cells), which display a temperature-sensitive defect in the acidification of endosomes, but not lysosomes. In G.7.1 and normal wild-type cells grown at the permissive temperature (34 degrees C), the lysosomal enzymes alpha-glucosidase and cathepsin D were synthesized as...

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Identifiers

PMID: 1849319
DOI: 10.1007/BF01232971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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