Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The receptor-recycling and lysosome biogenesis mutant TfT1.11 belongs to a new complementation group, End6.

Somatic cell and molecular genetics - 1 Jan 1994

Bucci M, Moyer T W, Brown C M, Wilson R B, Murphy R F

Abstract excerpt

We have previously isolated a Chinese hamster ovary (CHO) mutant with a temperature-dependent pleiotropic defect in receptor recycling. This mutant, TfT1.11, has also been shown to have defects in fluid-phase endocytosis and lysosome biogenesis. Previously isolated CHO cell mutants with defects in endocytosis have been assigned to five recessive complementation groups (End1-End5). We have performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CHO Cells
Share to Cricetinae
Share to Cricetulus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Lethal

Share to Genetic Complementation Test

Share to Hybrid Cells

Share to Mutation

Share to Phenotype

Source

Identifiers

PMID: 8197476
DOI: 10.1007/BF02257485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The receptor-recycling and lysosome biogenesis mutant TfT1.11 belongs to a new complementation group, End6.PMID 8197476Read ↗

Slowed receptor trafficking in mutant CHO lines of the End1 and End2 complementation groups.Semantic proximity Read ↗

The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected.Semantic proximity Read ↗

Isolation by fluorescence-activated cell sorting of Chinese hamster ovary cell lines with pleiotropic, temperature-conditional defects in receptor recycling.Semantic proximity Read ↗

Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells.Semantic proximity Read ↗

Recovery of function in Chinese hamster ovary cell mutants with temperature-sensitive defects in vacuolar acidification.Semantic proximity Read ↗

Disruptions in Golgi structure and membrane traffic in a conditional lethal mammalian cell mutant are corrected by epsilon-COP.Semantic proximity Read ↗

Novel method for isolating mammalian cells defective in fluid-phase endocytosis.Semantic proximity Read ↗

Defective transport of Sindbis virus glycoproteins in End4 mutant Chinese hamster ovary cells.Semantic proximity Read ↗

Isolation of NPC1-deficient Chinese hamster ovary cell mutants by gene trap mutagenesis.Semantic proximity Read ↗

Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis.Semantic proximity Read ↗

Isolation of three classes of conditional lethal Chinese hamster ovary cell mutants with temperature-dependent defects in low density lipoprotein receptor stability and intracellular membrane transport.Semantic proximity Read ↗

end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.