Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells.

The Journal of biological chemistry - 25 Nov 1990

Wang R H, Colbaugh P A, Kao C Y, Rutledge E A, Draper R K

Abstract excerpt

Mutant V.24.1 defines the End4 complementation group of temperature-sensitive Chinese hamster ovary cell mutants selected for resistance to protein toxins. We investigated the secretory pathway in the mutant cells and found: 1) The hemagglutinin of influenza virus failed to reach the plasma membr...

Topics

Animals
Cell Line
Cricetinae
Cricetulus
Endocytosis
Female
Genetic Complementation Test
Horseradish Peroxidase
Kinetics
Lysosomes
Mutation
Ovary
Protein Biosynthesis
Proteins
Temperature
beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 2122970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2122970-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics