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Article

Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma.

International journal of cancer - 2 Jan 1994

Schlegel J, Merdes A, Stumm G, Albert F K, Forsting M, Hynes N, Kiessling M

Abstract excerpt

The objective of our study was to determine the frequency of EGF-receptor-gene rearrangement in relation to tumour-growth behaviour in an unselected group of glioma patients. We investigated 73 glial tumours with different grades of malignancy (17 low-grade gliomas, 14 anaplastic variants, and 42 GBM) by Southern analysis, reverse transcriptase PCR (RT-PCR) amplification of mRNA, and Western analysis. An...

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Identifiers

PMID: 8262681
DOI: 10.1002/ijc.2910560114

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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