Article
Epidermal growth factor receptor gene expression in high grade gliomas.
Folia neuropathologica - 1 Jan 2011
Larysz Dawid, Kula Dorota, Kowal Monika, Rudnik Adam, Jarząb Michał, Blamek Sławomir, Bierzyńska-Macyszyn Grażyna, Kowalska Małgorzata, Bażowski Piotr, Jarząb Barbara
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) gene amplification and protein expression in malignant gliomas (anaplastic astrocytoma, AA and glioblastoma, GBL) were suggested to be correlated with the degree of malignancy. Large deletions within the EGFR gene occur frequently in glioma patients. The aim of our study was to analyse EGFR gene expression by real-time PCR by three different amplicons located...
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