Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.

Abstract excerpt

Several types of epidermal growth factor receptor (EGFR) gene mutations have been reported in glioblastomas, and in nearly all cases the alterations have been reported in tumors with EGFR amplification. The objectives of this study were to determine the frequency and diversity of EGFR mutations in glioblastomas and to determine whether gene mutation is inevitably associated with increased EGFR gene dosage. To...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Glioblastoma
• Share to Brain Neoplasms
• Share to ErbB Receptors