Article
Prognostic significance of p53 gene alterations in node-negative breast cancer.
Breast cancer research and treatment - 1 Jan 1993
Elledge R M, Fuqua S A, Clark G M, Pujol P, Allred D C, McGuire W L
Abstract excerpt
UNLABELLED: Mutations in the p53 gene can play a role in the transformation of normal to malignant cells. Because these mutations are more frequently reported later in the course of transformation, their presence could reflect a greater malignant potential of the tumor and, thus, an increased pro...
Topics
- Base Sequence
- Breast Neoplasms
- Codon
- DNA, Neoplasm
- DNA, Single-Stranded
- Exons
- Female
- Genes, p53
- Humans
- Lymphatic Metastasis
- Middle Aged
- Multivariate Analysis
- Mutation