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Article

TP53 and MYC gene alterations independently predict poor prognosis in breast cancer patients.

Genes, chromosomes & cancer - 1 Jul 1996

Berns E M, Klijn J G, Smid M, van Staveren I L, Look M P, van Putten W L, Foekens J A

Abstract excerpt

We intended to establish the frequency of exon-specific TP53 gene alterations and the relation to patient and tumor characteristics and clinical outcome of patients with breast cancer. By using polymerase chain reaction-single-strand conformation polymorphism analysis (PCR-SSCP) and sequencing techniques, TP53 gene alterations were found in 59 (32%) of the 187 samples studied. Most of the TP53 changes (37%) were...

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Source

Identifiers

PMID: 8814449
DOI: 10.1002/(SICI)1098-2264(199607)16:3<170::AID-GCC3>3.0.CO;2-W

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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