Correlation between mutation in P53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma.

Article

Correlation between mutation in P53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma.

Blood - 15 Nov 1997

Koduru P R, Raju K, Vadmal V, Menezes G, Shah S, Susin M, Kolitz J, Broome J D

Abstract excerpt

In the biology of a cell, the central role of p53 in controlling functions such as G1/S transition (check point) and DNA damage repair, and as a trigger of apoptosis, is well established. Somatic mutations or other changes in P53 have been reported in numerous tumor types, and in some of these, t...

Topics

Amino Acid Sequence
Biomarkers, Tumor
Humans
Lymphoma, B-Cell
Molecular Sequence Data
Mutation
Survival Analysis
Tumor Suppressor Protein p53

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