Article
Prognostic value of P53 gene mutations in a large series of node-negative breast cancer patients.
Cancer research - 1 Apr 1998
Falette N, Paperin M P, Treilleux I, Gratadour A C, Peloux N, Mignotte H, Tooke N, Löfman E, Inganäs M, Bremond A, Ozturk M, Puisieux A
Abstract excerpt
The most important subgroup of breast cancer patients for which reliable prognostic factors are needed are women without axillary lymph node involvement. Although overall, these patients have a good prognosis, it is known that 20-30% will experience a recurrence of the disease. To determine the prognostic significance of P53 tumor suppressor gene mutation, specimens from 113 primary breast cancers were evaluated...
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