Article
TP53 and oesophageal cancer.
Pathologie-biologie - 1 Dec 1997
Ferec C, Giroux M A, Audrezet M P, Robaszkiewicz M
Abstract excerpt
Mutations of the tumor suppressor gene TP53 have been detected in tumor tissues of a large variety of human malignancies and contribute to the development, progression and probably the prognosis of the disease. The pattern of somatic mutations in the TP53 gene in human tumors most often consists of a point mutation in one allele accompanied by loss or rearrangement of the second allele. Esophageal cancer is one...
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