A potential laboratory test for dysplastic nevus syndrome: ultraviolet hypermutability of a shuttle vector plasmid.

doi:10.1111/1523-1747.ep12388847

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Article

A potential laboratory test for dysplastic nevus syndrome: ultraviolet hypermutability of a shuttle vector plasmid.

The Journal of investigative dermatology - 1 Jul 1994

Moriwaki S, Tarone R E, Kraemer K H

Abstract excerpt

The diagnosis of the melanoma-prone disorder dysplastic nevus syndrome (DNS) is based currently on a combination of clinical and histopathologic examinations of patients. To develop a potential laboratory test for DNS, we utilized the observation that an ultraviolet light (UV)-treated mutagenesis...

Topics

Diagnostic Tests, Routine
Dysplastic Nevus Syndrome
Genes, Suppressor
Genetic Vectors
Humans
Mutation
Plasmids
RNA, Transfer
Ultraviolet Rays

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