Article
XPA protein alters the specificity of ultraviolet light-induced mutagenesis in vitro.
Environmental and molecular mutagenesis - 1 Jan 2001
King N M, Oakley G G, Medvedovic M, Dixon K
Abstract excerpt
Studies of ultraviolet (UV) light mutagenesis have demonstrated mutations at common sites in the target genes of shuttle vector plasmids replicated in cultured cells or by cellular extracts. The reasons for the specific pattern of mutagenesis are largely unknown. We have examined the specificity of UV-induced mutagenesis by replicating plasmid pLS189, irradiated with 40 J/m(2) UVC or unirradiated, in either...
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