Article
Similarity in the molecular profile of mutations induced by UV light in shuttle vector plasmids propagated in mouse and human cells.
Mutagenesis - 1 Jan 1994
Yagi T, Sato M, Nishigori C, Takebe H
Abstract excerpt
Shuttle vector plasmids pYZ289 were irradiated with UV and transfected to mouse cells to permit repair of damage, mutation and replication in the cells. The frequency and types of mutations were compared with those of UV-irradiated shuttle vector plasmids pZ189 which were propagated in normal human and xeroderma pigmentosum (XP) patient cells defective in DNA repair. Both shuttle vector plasmids contain a...
Topics
- Animals
- Base Sequence
- Cell Line
- DNA Repair
- Escherichia coli
- Genes, Bacterial
- Genes, Suppressor
- Genetic Vectors
- Humans
- Mice
- Molecular Sequence Data
- Mutagenesis
