Improved sib-pair linkage test for disease susceptibility loci.

doi:10.1002/gepi.1370100403

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Article

Improved sib-pair linkage test for disease susceptibility loci.

Genetic epidemiology - 1 Jan 1993

Faraway J J

Abstract excerpt

An improved sib-pair test for linkage is introduced which is superior to the previously proposed tests. The test is derived from the standard chi-squared goodness of fit statistic by restricting the alternative hypothesis to the genetically possible. Critical values are given and exact power comp...

Topics

Alleles
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Humans
Statistics as Topic

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