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Article

Combined linkage and association mapping of quantitative trait loci by multiple markers.

Genetics - 1 Jun 2005

Jung Jeesun, Fan Ruzong, Jin Lei

Abstract excerpt

Using multiple diallelic markers, variance component models are proposed for high-resolution combined linkage and association mapping of quantitative trait loci (QTL) based on nuclear families. The objective is to build a model that may fully use marker information for fine association mapping of QTL in the presence of prior linkage. The measures of linkage disequilibrium and the genetic effects are incorporated...

Topics

Alleles
Asthma
Chromosome Mapping
Family Health
Genetic Linkage
Genetic Markers
Humans
Likelihood Functions
Models, Statistical
Quantitative Trait Loci
Regression Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15802526
DOI: 10.1534/genetics.104.035147
PMCID: PMC1450431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15802526-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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