Two-locus developments of the weighted pairwise correlation method for linkage analysis.

doi:10.1002/(SICI)1098-2272(1998)15:5<491::AID-GEPI4>3.0.CO;2-3

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Article

Two-locus developments of the weighted pairwise correlation method for linkage analysis.

Genetic epidemiology - 1 Jan 1998

Zinn-Justin A, Abel L

Abstract excerpt

Different studies of complex traits assumed to be influenced by two unliked loci found that two-locus linkage analysis is more powerful than the classical one-locus strategy. The Weighted Pairwise Correlation (WPC) approach is a nonparametric method for linkage analysis that has the advantage to...

Topics

Alleles
Genetic Linkage
Genetic Markers
Genotype
Humans
Models, Genetic

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