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Article

Two-locus developments of the weighted pairwise correlation method for linkage analysis.

Genetic epidemiology - 1 Jan 1998

Zinn-Justin A, Abel L

Abstract excerpt

Different studies of complex traits assumed to be influenced by two unliked loci found that two-locus linkage analysis is more powerful than the classical one-locus strategy. The Weighted Pairwise Correlation (WPC) approach is a nonparametric method for linkage analysis that has the advantage to analyze any kind of phenotypes and to consider extended pairs of relatives. In this report, we propose different...

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PMID: 9728891
DOI: 10.1002/(SICI)1098-2272(1998)15:5<491::AID-GEPI4>3.0.CO;2-3

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