Article
Genetic analysis of carcinogen enhancement of type 5 adenovirus transformation of cloned Fischer rat embryo fibroblast cells.
Molecular carcinogenesis - 1 Jan 1993
Su Z Z, Shen R, Young C S, Fisher P B
Abstract excerpt
Pretreatment of CREF cells with methyl methanesulfonate (MMS) before infection with the host-range cold-sensitive type 5 adenovirus (Ad5) mutant H5hr1 results in a dose-dependent carcinogen enhancement of viral transformation (CET). The properties of CET observed with H5hr1, which include both an...
Topics
- Adenoviridae
- Animals
- Base Sequence
- Cell Transformation, Viral
- Clone Cells
- DNA, Viral
- Gene Expression Regulation
- Methyl Methanesulfonate
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Rats
- Rats, Inbred F344