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Article

Retransformation of a revertant cell line with the adenovirus E1 oncogenes and vanadate.

Journal of cellular biochemistry - 1 Jul 1990

Dessureault J, Weber J M

Abstract excerpt

We have isolated a revertant cell line (G5) from an adenovirus transformed rat cell line (F4) which failed to express the integrated viral oncogenes. To determine whether the reversion mutation was acting in cis or trans the G5 cells were co-transfected with an E1 gene bearing expression plasmid and a neomycin phosphotransferase bearing plasmid. G418-resistant colonies were picked and shown to express the E1...

Topics

Adenoviridae
Animals
Cell Line, Transformed
Cell Transformation, Neoplastic
Cell Transformation, Viral
Mutation
Oncogenes
Rats
Vanadates

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2380267
DOI: 10.1002/jcb.240430309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2380267-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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