Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants.

doi:10.1093/mutage/11.1.89

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Article

Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants.

Mutagenesis - 1 Jan 1996

Arnold W R, Rainbow A J

Abstract excerpt

In this study we have utilized the ability of rodent cells to replicate viral DNA following semi-permissive infection by human adenovirus (Ad) to examine the host cell reactivation (HCR) of radiation-damaged Ad in several UV-sensitive Chinese hamster ovary (CHO) cell mutants. A significant reduct...

Topics

Adenoviruses, Human
Animals
CHO Cells
Cricetinae
DNA Damage
DNA Repair
DNA Replication
DNA, Viral
Humans
Mutation
Radiation Tolerance
Ultraviolet Rays

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