Article
Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants.
Mutagenesis - 1 Jan 1996
Arnold W R, Rainbow A J
Abstract excerpt
In this study we have utilized the ability of rodent cells to replicate viral DNA following semi-permissive infection by human adenovirus (Ad) to examine the host cell reactivation (HCR) of radiation-damaged Ad in several UV-sensitive Chinese hamster ovary (CHO) cell mutants. A significant reduction in HCR of viral DNA synthesis for UV-irradiated Ad was detected in a series of UV-sensitive mutants from...
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