Article
Low frequency of the p53 gene mutations in neuroblastoma.
Cancer - 15 Jun 1994
Hosoi G, Hara J, Okamura T, Osugi Y, Ishihara S, Fukuzawa M, Okada A, Okada S, Tawa A
Abstract excerpt
BACKGROUND: The p53 gene frequently is affected by point mutations, rearrangements, or deletions that contribute to the genesis or progression of a wide variety of human adult solid tumors; however, to the authors' knowledge, this gene alteration has not been analyzed in neuroblastoma. METHODS: G...
Topics
- Child
- Child, Preschool
- Exons
- Female
- Gene Amplification
- Genes, myc
- Genes, p53
- Humans
- Infant
- Infant, Newborn
- Male
- Mutation
- Neuroblastoma
- Point Mutation