Article

Tools development for the investigation of p53 in neuroblastoma

2010-01-01

Abstract excerpt

The tumour suppressor p53 is a transcription factor which is mutated in over 50% of adult human cancers. However, it is rarely mutated in primary neuroblastoma, nor in a number of other childhood cancers. Neuroblastomais a cancer derived from precursor cells of the peripheral sympathetic nervous system, apparently occurring due to a lack of differentiation of neuronalcrest cells. It is the most commonsolid extra-c...

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Literature Corpus work: 86a8ee93-8465-540b-8261-e2a964df99f3
DOI: 10.17638/03061720

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