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Article

P73 expression in neuroblastoma: a role in the biology of advanced tumors?

Pediatric hematology and oncology - 1 Jan 2000

Matos P, Isidro G, Vieira E, Lacerda A F, Martins A G, Boavida M G

Abstract excerpt

p73, a recently identified gene showing high homology to p53 and mapping to 1p36.33, was presented as a candidate gene for neuroblastoma. In this study the authors evaluate the levels and allelic nature of p73 expression in primary neuroblastomas using reverse transcription-polymerase chain reaction-restriction fragment length polymorphism strategies based on intragenic polymorphisms. From 32 neuroblastoma...

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Source

Identifiers

PMID: 11205839
DOI: 10.1080/088800101750059846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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P73 expression in neuroblastoma: a role in the biology of advanced tumors?PMID 11205839Read ↗

Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.Semantic proximity Read ↗

Stage-independent expression and genetic analysis of tp73 in neuroblastoma.Semantic proximity Read ↗

p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequentSemantic proximity Read ↗

Genomic and allelic expression status of the p73 gene in human neuroblastoma.Semantic proximity Read ↗

Differential expression and allelotyping of the p73 gene in neuroblastoma.Semantic proximity Read ↗

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.Semantic proximity Read ↗

Variable expression and absence of mutations in p73 in primary neuroblastoma tumors argues against a role in neuroblastoma development.Semantic proximity Read ↗

Expression of ΔNp73 is a molecular marker for adverse outcome in neuroblastoma patientsSemantic proximity Read ↗

p73, a gene related to p53, is not mutated in esophageal carcinomas.Semantic proximity Read ↗

Low frequency of the p53 gene mutations in neuroblastoma.Semantic proximity Read ↗

The expression of p73 is increased in lung cancer, independent of p53 gene alteration.Semantic proximity Read ↗

Elevated and biallelic expression of p73 is associated withprogression of human bladder cancer.Semantic proximity Read ↗

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