Article
The TP53 gene rs1042522 C>G polymorphism and neuroblastoma risk in Chinese children.
Aging - 8 Mar 2017
He Jing, Wang Fenghua, Zhu Jinhong, Zhang Zhuorong, Zou Yan, Zhang Ruizhong, Yang Tianyou, Xia Huimin
Abstract excerpt
TP53, a tumor suppressor gene, plays a critical role in cell cycle control, apoptosis, and DNA damage repair. Previous studies have indicated that the TP53 gene Arg72Pro (rs1042522 C>G) polymorphism is associated with susceptibility to various types of cancer. We evaluated the association of the TP53 gene rs1042522 C>G polymorphism with neuroblastoma susceptibility in a hospital-based study among the Chinese Han...
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