Article
Aberrant CpG island methylation in early-onset sporadic gastric carcinoma.
Journal of cancer research and clinical oncology - 1 Nov 2005
Kim Hee Cheol, Kim Jin Cheon, Roh Sun Ae, Yu Chang Sik, Yook Jeong Hwan, Oh Sung Tae, Kim Byung Sik, Park Kun Choon, Chang Rin
Abstract excerpt
PURPOSE: Gastric carcinoma more commonly affects older patients, and it is thought that cases of early-onset gastric carcinoma may develop with a different molecular profile different from that of carcinoma occurring at a later age. We assayed the methylation status and genetic changes in genes associated with the APC-beta-catenin axis and the mismatch repair system in relatively early-onset gastric carcinoma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
