K-ras codon 12 mutations in biliary tract tumors detected by polymerase chain reaction denaturing gradient gel electrophoresis.

doi:10.1002/1097-0142(19940601)73:11<2727::aid-cncr2820731113>3.0.co;2-#

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Article

K-ras codon 12 mutations in biliary tract tumors detected by polymerase chain reaction denaturing gradient gel electrophoresis.

Cancer - 1 Jun 1994

Imai M, Hoshi T, Ogawa K

Abstract excerpt

BACKGROUND: Although the prevalence of K-ras codon 12 mutations in biliary tract (BT) tumors has been addressed in previous studies, the results have shown large discrepancies in mutation frequency. METHODS: K-ras codon 12 mutations were investigated by polymerase chain reaction (PCR)-denaturing...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Bile Duct Neoplasms
Bile Ducts, Extrahepatic
Codon
DNA, Neoplasm
Electrophoresis
Female
Gallbladder Neoplasms
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

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