Article
K-ras codon 12 and p53 mutations in biopsy specimens and bile from biliary tract cancers.
Pathology international - 1 Jan 1999
Itoi T, Takei K, Shinohara Y, Takeda K, Nakamura K, Horibe T, Sanada A, Ohno H, Matsubayashi H, Saito T, Watanabe H
Abstract excerpt
To evaluate whether it is useful for diagnosis to detect K-ras and p53 mutations in biopsy specimens and bile of biliary tract lesions, 12 cholangiocarcinomas (CC), eight cases of cholangitis, seven gallbladder carcinomas (GBC), seven gallbladder cholesterol polyps, four cases of adenomyomatosis of the gallbladder and five cases of cholecystitis were examined. K-ras and p53 mutations in bile were detected by a...
Topics
- Base Sequence
- Bile
- Biliary Tract
- Biliary Tract Neoplasms
- Biopsy
- Codon
- DNA, Neoplasm
- Genes, p53
- Genes, ras
- Humans
- Immunohistochemistry