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Article

Usefulness of p53 gene mutations in the supernatant of bile for diagnosis of biliary tract carcinoma: comparison with K- ras mutation.

Journal of gastroenterology - 1 Jan 2002

Wang Ying, Yamaguchi Yasushi, Watanabe Hiroyuki, Ohtsubo Koushiro, Wakabayashi Tokio, Sawabu Norio

Abstract excerpt

BACKGROUND: The sensitivity of bile cytology for the diagnosis of biliary tract carcinoma (BTCa) is still low. In addition, the incidence of detection of genetic mutations in the bile of BTCa is not satisfactory yet. To improve the molecular diagnosis of BTCa, we analyzed p53 and K- ras mutations in DNA extracted from not only the sediment but the supernatant of bile samples. METHODS: Polymerase chain...

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Identifiers

PMID: 12424567
DOI: 10.1007/s005350200137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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