Article
Mutational spectrum of K-ras oncogene among Indian patients with gallbladder cancer.
Journal of gastroenterology and hepatology - 1 Aug 2004
Singh Mahendra Kumar, Chetri Kamal, Pandey Udai Bhan, Kapoor Vinay Kumar, Mittal Balraj, Choudhuri Gourdas
Abstract excerpt
BACKGROUND AND AIM: Gallbladder cancer (GBC) is a common abdominal malignancy in India with an obscure etiology. However, long-standing stones and chronic infection in gallbladder have been suspected as possible etiologic factors. As carcinogenesis complicating chronic inflammation proceeds through the stages of dysplasia and metaplasia, mutation in the K-ras gene may be an important marker for GBC. The aim of...
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