Article
[Frequency of K-ras mutation in biliary and pancreatic tumors].
Revista medica de Chile - 1 Dec 2005
Roa Juan Carlos, Anabalón Leonardo, Tapia Oscar, Melo Angélica, de Aretxabala Xabier, Roa Iván
Abstract excerpt
BACKGROUND: The ras gene family (H-ras, N-ras and K-ras) are oncogenes that mutate frequently in human cancer, specially in tumors of the biliary tract and pancreas. AIM: To determine the frequency of K-ras gene codon 12 mutation in pancreatic and biliary tumors. MATERIAL AND METHODS: Samples of 35 gallbladder, 15 ampulla of Vater, 10 biliary tract and 9 pancreatic tumors, were analyzed. The tumor tissue was...
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