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Article

Diagnostic utility of K-ras mutational analysis on bile obtained by endoscopic retrograde cholangiopancreatography.

Gastrointestinal endoscopy - 1 Oct 1995

Lee J G, Leung J W, Cotton P B, Layfield L J, Mannon P J

Abstract excerpt

BACKGROUND: Because K-ras oncogene mutations are present in more than 90% of pancreaticobiliary tumors, we tested prospectively whether K-ras mutational analysis of bile samples obtained during ERCP was superior to conventional bile cytology for diagnosis of malignancy. METHODS: Bile samples from...

Topics

Bile
Biliary Tract Neoplasms
Cholangiopancreatography, Endoscopic Retrograde
DNA Mutational Analysis
Genes, ras
Mutation
Pancreatic Neoplasms
Polymerase Chain Reaction
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8536899
DOI: 10.1016/s0016-5107(95)70129-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8536899-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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