Article
Patterns of K-ras codon 12 and 13 mutations found in pancreatic adenocarcinoma of 30 Chinese patients by microdissection, PCR and direct sequencing.
Journal of gastroenterology and hepatology - 1 Jan 2005
Wei Shuanzeng, Liang Zhiyong, Gao Jie, Wu Shafei, Zhu Hong, Liu Hongrui, Liu Tonghua
Abstract excerpt
BACKGROUND AND AIM: To our knowledge there are few reports on the K-ras mutation pattern of pancreatic adenocarcinoma from Chinese mainland patients. We examined surgically resected formalin-fixed, paraffin-embedded primary pancreatic adenocarcinoma tissue blocks for the presence of activating point mutations at codon 12 and 13 of the K-ras gene. METHODS: Mutations were detected through the use of...
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