Article
K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder.
Journal of surgical oncology - 1 Dec 2000
Kim S W, Her K H, Jang J Y, Kim W H, Kim Y T, Park Y H
Abstract excerpt
BACKGROUND AND OBJECTIVES: To determine whether K-ras mutation plays any role in the development and progression of gallbladder cancer, or has any clinical or pathological significance in gallbladder cancer patients, we investigated the presence and incidence of this mutation in the normal mucosa, and precancerous and cancerous lesions of the gallbladder. METHODS: DNA was obtained from normal mucosa, dysplastic...
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