Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer.

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Article

Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer.

Cancer research - 1 Mar 1995

Gao X, Zacharek A, Salkowski A, Grignon D J, Sakr W, Porter A T, Honn K V

Abstract excerpt

A putative tumor suppressor gene, the BRCA1 gene, on chromosome 17q21 has recently been identified and shown to be mutated in breast and ovarian cancers. We have undertaken the present study to explore the possible involvement of the BRCA1 and/or other potential genes on chromosome 17q in prostat...

Topics

Adenocarcinoma
Alleles
Base Sequence
Chromosomes, Human, Pair 17
DNA, Neoplasm
DNA, Satellite
Gene Deletion
Genes, Tumor Suppressor
Heterozygote
Humans
Male
Molecular Sequence Data
Polymerase Chain Reaction
Prostatic Neoplasms

Source

Open in PubMed

Identifiers

PMID: 7866981

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7866981-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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