Article
Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.
Gene - 8 Apr 1994
Cafferkey R, McLaughlin M M, Young P R, Johnson R K, Livi G P
Abstract excerpt
The yeast TOR1 (DRR1) and TOR2 (DRR2) proteins are putative targets of the immunosuppressive drug rapamycin (Rm), defined by dominant drug-resistance mutations. They share a large C-terminal domain that exhibits sequence similarity to the 110-kDa subunit of phosphatidylinositol (PI) 3-kinases. In this report, we present an amino acid (aa) sequence alignment of TOR1 (DRR1) and TOR2 (DRR2) and identify conserved...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Fungal Proteins
- Genes, Fungal
- Molecular Sequence Data
- Phosphatidylinositol 3-Kinases
- Phosphotransferases (Alcohol Group Acceptor)
- Point Mutation
- Saccharomyces cerevisiae