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Article

Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.

Gene - 8 Apr 1994

Cafferkey R, McLaughlin M M, Young P R, Johnson R K, Livi G P

Abstract excerpt

The yeast TOR1 (DRR1) and TOR2 (DRR2) proteins are putative targets of the immunosuppressive drug rapamycin (Rm), defined by dominant drug-resistance mutations. They share a large C-terminal domain that exhibits sequence similarity to the 110-kDa subunit of phosphatidylinositol (PI) 3-kinases. In this report, we present an amino acid (aa) sequence alignment of TOR1 (DRR1) and TOR2 (DRR2) and identify conserved...

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PMID: 8163165
DOI: 10.1016/0378-1119(94)90141-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs.PMID 8163165Read ↗

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