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Article

The TOR signaling cascade regulates gene expression in response to nutrients.

Genes & development - 15 Dec 1999

Cardenas M E, Cutler N S, Lorenz M C, Di Como C J, Heitman J

Abstract excerpt

Rapamycin inhibits the TOR kinases, which regulate cell proliferation and mRNA translation and are conserved from yeast to man. The TOR kinases also regulate responses to nutrients, including sporulation, autophagy, mating, and ribosome biogenesis. We have analyzed gene expression in yeast cells exposed to rapamycin using arrays representing the whole yeast genome. TOR inhibition by rapamycin induces expression...

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Identifiers

PMID: 10617575
DOI: 10.1101/gad.13.24.3271
PMCID: PMC317202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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