Article
Hepatitis B virus C gene heterogeneity in a familial cluster of anti-HBc negative chronic carriers.
Journal of medical virology - 1 Feb 1994
Fiordalisi G, Primi D, Tanzi E, Magni E, Incarbone C, Zanetti A R, Cariani E
Abstract excerpt
We studied a familial cluster of adult HBV chronic carriers characterized by serological markers of active viral replication, normal or slightly elevated ALT levels and, in four out of five cases, absence of anti-HBc reactivity. The nucleotide sequence of the pre-C/C region of HBV was analyzed in...
Topics
- Adolescent
- Adult
- Base Sequence
- Carrier State
- Cloning, Molecular
- Cluster Analysis
- Female
- Frameshift Mutation
- Genes, Viral
- Genetic Variation
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Middle Aged